Couples looking for in vitro fertilization (IVF) can rely on genetic testing from experienced IVF treatment providers. Genetic testing increases the chances of IVF success by assessing embryos to identify genetic and chromosomal challenges before transferring the embryo to the uterus. This helps in selecting the healthiest embryo for implantation. Here is more information about the role of genetic testing in IVF failure:
Aneuploidy Screening
Aneuploidy, characterized by abnormal chromosome numbers and structures, is among the issues that could develop when individuals grow older. For women, increasing age influences a decline in egg quality. This increases the likelihood of making embryos that have abnormal chromosomes.
The variation in chromosomes may lead to miscarriage and other fertility challenges that make it harder to conceive naturally. Men may also experience a drop in sperm quality. This makes genetic errors and IVF failure more likely. Experienced infertility treatment providers can use preimplantation genetic testing. This approach lets doctors choose embryos with the right number of chromosomes to enhance the chances of a successful pregnancy.
Single Gene Disorder Testing
Single gene disorder testing focuses on disorders involving mutations that affect a particular gene. These disorders include cystic fibrosis, Huntington’s disease, and sickle-cell anemia. Genetic IVF assessment helps select embryos that are void of single gene disorders for transferring. This helps prevent the transmission of the disorder to the newborn.
Preimplantation Genetic Testing
You can detect certain types of chromosomal abnormalities using preimplantation genetic testing for structural chromosomal rearrangement. Individuals with these chromosomal abnormalities may experience recurring pregnancy loss. Reputable IVF treatment providers offer genetic counseling before they screen embryos through preimplantation genetic testing. This helps clients know more about the chromosomal abnormalities or genetic problems that the embryos are getting screened for.
Genetic Blood Disorder Testing
Genetic testing can help identify thalassemia. This is a blood disorder that has a high likelihood of affecting the newborn when both parents are carriers. Genetic testing lets doctors identify embryos that are not carrying thalassemia. This improves the chances of a successful pregnancy and lowers the risk of transmission.
Mosaicism Testing
Mosaicism happens when an embryo comprises more than one cell type. Every cell type has a unique profile. Some cells may possess an abnormal number of chromosomes, while others have a normal number. Through genetic testing, doctors can make informed choices so they can select a healthy embryo, increasing the chances of a successful pregnancy.
Monogenetic Disorder Testing
Genetic testing for monogenetic challenges entails screening to check for a particular inheritable condition in the embryo. This solution can be suitable where a partner or both partners show a family history of genetic disorders. You can use monogenetic disorder testing to assess the presence of autosomal disorders, dominant disorders like Marfan syndrome, recessive disorders, and X-linked diseases like hemophilia A and B.
Comparative Genomic Hybridization Testing
Comparative genomic hybridization (CGH) testing is a genetic test that helps detect the number of chromosomes and imbalances in their structure. The CGH test involves comparing chosen DNA with another DNA for reference and labeling them using varying fluorescent dyes. When mixed using a slide, the DNAs bind to the complementary sequences. They then use a scanner to assess the intensity of the fluorescent dyes. CGH tests are useful in identifying aneuploidy, abnormal chromosome numbers, or Turner syndrome. The test could also help identify structural abnormalities such as deletions, translocations, and chromosome duplication that influence several genes and increase the risk of developmental challenges.
Next-Generation Sequence Testing
Next-generation sequencing enables fast sequencing of large capacities of DNA. This testing technique facilitates the assessment of a genome’s whole embryo to reveal every genetic adaptation. It aids in the identification of likely genetic disorders and the selection of the best embryos to implant. Next-generation sequencing helps pinpoint anomalies that could cause miscarriage or health challenges in children.
Use Genetic Testing To Prevent IVF Failure Today
Genetic testing from established IVF treatment providers helps increase the possibility of a successful pregnancy. Reputable providers offer counseling and specific information to help you learn more about a testing procedure. Genetic IVF testing offers a path to a healthy pregnancy by lowering the chances of genetic issues. Contact an IVF treatment provider to learn more about genetic testing today.